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In the context of the microbiome, a number of bacteria have been implicated in the process of citrullination Porphyromonas gingivalis, a bacterium associated with periodontitis 33, the hypercitrullination of neutrophils as part of the immune system response to such proteins Aggregatibacter actinomycetemcomitans 34, in molecular mimicry Escherichia coli and Proteus mirabilis 31 and in the production of antibodies by B lymphocytes which mediate the autoimmune response Epstein Barr virus 35 buy priligy paypal